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Terminolic acid

CAS No. 564-13-6

Terminolic acid ( 2α,6β,23-trihydroxyl oleanolic acid )

Catalog No. M24552 CAS No. 564-13-6

Terminolic acid is a pentacyclic triterpenoid glucoside isolated from Combretum racemosum,?can inhibit the pro-inflammatory cytokines by binding to receptor active site of IL-1β and IL-6, and enhance anti-inflammatory cytokines by binding to IL-4 receptor binding sites.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Terminolic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Terminolic acid is a pentacyclic triterpenoid glucoside isolated from Combretum racemosum,?can inhibit the pro-inflammatory cytokines by binding to receptor active site of IL-1β and IL-6, and enhance anti-inflammatory cytokines by binding to IL-4 receptor binding sites.
  • Description
    Terminolic acid is a pentacyclic triterpenoid glucoside isolated from Combretum racemosum,?can inhibit the pro-inflammatory cytokines by binding to receptor active site of IL-1β and IL-6, and enhance anti-inflammatory cytokines by binding to IL-4 receptor binding sites. It?also exhibits moderate antibacterial activity.
  • Synonyms
    2α,6β,23-trihydroxyl oleanolic acid
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Bacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    564-13-6
  • Formula Weight
    504.7
  • Molecular Formula
    C30H48O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    C[C@@]12CC[C@]3(CCC(C[C@H]3C1=CC[C@H]4[C@]2(C[C@H]([C@@H]5[C@@]4(C[C@H]([C@@H]([C@@]5(C)CO)O)O)C)O)C)(C)C)C(=O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Legiawati L, et, al. In silico study of Centella asiatica active compounds as anti-inflammatory agent by decreasing Il-1 and Il-6 activity, promoting Il-4 activity. /J. Pharm. Sci. & Res. Vol. 10(9), 2018, 2142-2147.
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